Opened by J.W. Marriott, Jr., the company's then Chief Executive Officer who now serves as Chairman Emeritus, the Amsterdam Marriott Hotel debuted in Europe, boasting an unparalleled city center location. At the time of its construction, it was the city's largest hotel with 396 rooms.

Throughout its 50 years of operation, the hotel has remained true to its core values. With a blend of classic hospitality, strategic innovation, and a dedicated, close-knit team, the hotel has continued to be a reliable presence in an ever-changing city. Dozens of staff have remained with the hotel over the decades, some for 45 years, and the hotel has produced many future leaders for the company.