"The crew will travel to the orbiting laboratory on a new SpaceX Dragon spacecraft after launching on the company's Falcon 9 rocket. The targeted docking time is approximately 12:30 p.m. EDT (10:00 p.m. IST), Wednesday, June 11," NASA said in a statement.

ISRO Chairman V. Narayanan visited Axiom Space last week to review the preparations for the spaceflight.

The astronauts have been in quarantine since May 25 to prepare for the trip and have been training ahead of the launch on June 10.

"The #Ax4 crew undergoes extensive emergency training, featuring a range of scenarios such as underwater escape drills," Axiom Space said in a post on X, and shared a video of the training programme.

During the 14-day stay at the ISS, the Ax-4 crew is expected to interact with Prime Minister Narendra Modi, school students, and space industry leaders, among others.

Earlier this week, the crew addressed a press conference to give an update on the training ahead of the launch. "We are good for the launch, we have completed all the training and the team has bonded well," Mr. Whitson said on Tuesday.